CRISPR-Cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

CRISPR-Cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome? by removing, adding or altering sections of the DNA? sequence. It is currently the simplest, most versatile and precise method of genetic manipulation and is therefore causing a buzz in the science world. The CRISPR-Cas9 system consists of two key molecules that introduce a change (mutation?) into the DNA. These are: an enzyme? called Cas9. This acts as a pair of ‘molecular scissor...
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Thermo Fisher Scientific Custom Cell Engineering Service

The task of generating cell lines, parental cell lines, high throughput-ready cells and other tools for your cell-based discovery projects can be greatly simplified with custom cell engineering tools from Life Technologies. Complete your cell engineering projects in far less time by collaborating with our Custom Biology Services team. Whether your research requires engineered or Jump-In™ parental cell lines; BacMam virus particles or validated, high-throughput screening-ready cells in large-s...
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UCLA scientists identify a new way to activate stem cells to make hair grow

UCLA researchers have discovered a new way to activate the stem cells in the hair follicle to make hair grow. The research, led by scientists Heather Christofk and William Lowry, may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy treatment. The research was published in the journal Nature Cell Biology. Hair follicle stem cells are long-lived cells in ...
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Researchers at Columbia University Medical Center (CUMC) and the University of North Carolina have developed skin patch that dissolves “Love Handles” in mice

Skin Patch Dissolves “Love Handles” in Mice Microneedle skin patch that delivers fat-shrinking drug locally could be used to treat obesity and diabetes Researchers have devised a medicated skin patch that can turn energy-storing white fat into energy-burning brown fat locally while raising the body’s overall metabolism. The patch could be used to burn off pockets of unwanted fat such as “love handles” and treat metabolic disorders, such as obesity and diabetes, according to researc...
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EVZIO is the first and only intelligent take-home naloxone auto-injection system with voice and visual guidance

EVZIO is the first and only intelligent take-home naloxone auto-injection system with voice and visual guidance—designed to help caregivers take fast, confident action administering naloxone in an opioid emergency. EVZIO can temporarily reverse the effects of opioids and help keep a patient breathing until emergency medical assistance is available Get emergency medical help right away after the first dose of EVZIO, even if the person wakes up If symptoms return after an injection ...
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Qualcomm’s New Virtual Reality App train to Diagnose Stroke – Think F.A.S.T. VR training: Improving stroke education and saving lives

  Strokes can happen to anyone at any time1 and the number of strokes young people experience is rising. In America, there was a 44% increase2 in the number of young adults hospitalized due to stroke over the last 10 years. Globally, it’s the second-leading cause of death3. Qualcomm Technologies (QTI) is helping medical practitioners and first responders diagnose strokes faster and in turn, reduce the long-term impact of the disease. We’ve collaborated with VR indu...
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RAVE- Robot Avatar Thermal Enhanced – will break the communication barrier that widely impacts many young children with minimal or no language and social interaction in early life.

Petitto Brain & Language Laboratory Completes Successful RAVE Pilot Launch The Petitto Brain & Language Laboratory, BL2, (Petitto, Scientific Director) has successfully piloted its RAVE ("Robot Avatar Thermal-Enhanced") prototype learning tool with 25 infants over the course of five days. The pilot was successfully executed between June 25 – 30, 2017. Insufficient minimal language exposure in very young children has been shown to have a devastating impact on these children’s ability ...
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HIDRATE SPARK 2.0 SMART BOTTLE THAT TRACKS YOUR HYDRATION AND ALERTS

Sometimes drinking more water is all we need to feel energized and brighten our mood. Available in an array of frosted colors, our sleek Hidrate Spark 2.0 smart water bottle will keep track of how much you drink and helps you meet your daily hydration goal. The Hidrate Spark 2.0 holds 24 fl oz (710 ml) and comes in five eye-catching colors. After many hours talking with potential customers just like you, we made the important decision to make the bottle with BPA-Free Titan plastic and without...
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Researchers at ETH Zurich in Switzerland have now developed a tiny, highly accurate acetone breath sensor that may soon serve as a core for fitness wearables and diabetes diagnostic devices

Researchers at ETH Zurich in Switzerland have now developed a tiny, highly accurate acetone breath sensor that may soon serve as a core for fitness wearables and diabetes diagnostic devices. Blow into the tube, please. In the future, the procedure will not just be used by police checking for alcohol intoxication, but also for testing the condition of athletes and for people who want to lose that extra bit of weight. A sensor developed by ETH researchers makes it possible to measure when the b...
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HOWARD HUGHES MEDICAL INSTITUTE – Whole Genome Sequencing Identifies New Genetic Signature for Autism

Autism has genetic roots, but most cases can’t be explained by current genetic tests. Now, patterns found in autistic children’s genomes – the complete set of genetic instructions inside cells – have revealed a new genetic signature for the disorder. The signature helps explain cases that don’t have other genetic markers of autism. The results, reported September 28, 2017, in the journal Cell, suggest that scanning a patient’s entire genome could help researchers better understand the suit...
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Imperial College London research suggest – Magic mushrooms may ‘reset’ the brains of depressed patients

Patients taking psilocybin to treat depression show reduced symptoms weeks after treatment following a 'reset' of their brain activity. The findings come from a study in which researchers from Imperial College London used psilocybin – the psychoactive compound that occurs naturally in magic mushrooms – to treat a small number of patients with depression in whom conventional treatment had failed. In a paper, published in the journal Scientific Reports, the researchers describe patient-reporte...
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Impossible Burger—a meatless patty made from plants, including wheat and potato protein

 It looks like a burger, it tastes like a burger but it is not beef. It's the Impossible Burger. When put on the grill, the patty sizzles. As it cooks, the unmistakeable smell of beef wafts through the air. After it's cooked, plated and served to the customer, the first bite is juicy. It looks like a burger, it tastes like a burger but it is not beef. It's the Impossible Burger The burger contains protein from wheat and potato, coconut oil and heme, an iron-containing compound. Soy ...
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‘SoClean’ CPAP sanitizer that is activated by oxygen (ozone or O3) to kill 99% of the mold, bacteria and viruses

The world's first automated CPAP cleaner and sanitizer The SoClean 2 is a quick and easy daily CPAP sanitizer. It uses activated oxygen (ozone or O3) to kill 99% of the mold, bacteria and viruses SoClean allows easier, more effective way to clean CPAP machine equipment. SoClean kills 99.9% of CPAP germs and bacteria in your mask, hose and reservoir with no disassembly, no water, and no chemicals in order to enhance your home CPAP experience. https://youtu.be/DSr4qls9vpo Just a drop...
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UNIVERSITY OF UTAH RESEARCHERS DEVELOP FASTER, MORE ACCURATE TEST FOR LIVER CANCER THAT CAN BE ADMINISTERED ANYWHERE

It’s estimated that about 788,000 people worldwide died of liver cancer in 2015, the second-leading cause of cancer deaths, according to the latest statistics from the World Health Organization. One of the major challenges in combatting this disease is detecting it early because symptoms often don’t appear until later stages. But a team of researchers led by University of Utah chemical engineering and chemistry professor Marc Porter and U surgeon and professor Courtney Scaife has developed a ...
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FDA cleared Xstat30 wound dressing, an expandable, multi-sponge dressing used to Stop Gun and Knife Wounds in Arms and Legs

U.S. Food and Drug Administration cleared the use of the XSTAT 30 wound dressing, an expandable, multi-sponge dressing used to control severe, life-threatening bleeding from wounds in areas that a tourniquet cannot be placed (such as the groin or armpit) in battlefield and civilian trauma settings. The clearance expands the device’s indication from use by the military only to use in adults and adolescents in the general population. Early control of severe bleeding may prevent shock and may be...
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Home Med Station medications organizing and aiding people in maintaining compliance in their medication schedule

The Home Med Station is the most convenient method for organizing and identifying a large number of regularly scheduled medications. By week, it indicates the time to take medications in four simple intervals daily. It has a helpful medicine sorting area, and there is even an area for weekly patient communications that can store 52 weeks of communication sheets. The patented features in the Home Med Station are designed to aid people in maintaining compliance in their medication schedule. It ha...
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Hexoskin smart shirt is capable of accurately tracking an array of biometric data. (cardiac, respiratory, sleep and activity data)

 Hexoskin Smart Shirts are a comfortable new way to monitor precise cardiac, respiratory, sleep and activity data. People with cardiovascular disease with a high cardiovascular risk (due to the presence of one or more risk factors such as hypertension, diabetes, hyperlipidemia or already established disease) need early detection and management using counseling and medicines, as appropriate. Hexoskin is an efficient and accurate solution to collect quantitative data about patients, every day,...
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High Dietary Energy Density (DED) foods may increase cancer risk regardless of obesity status

Dietary energy density (DED) is defined as the amount of available energy per unit of weight in the diet. It is generally expressed as kJ/g. Experimental studies in human subjects and a recent systematic review have shown that the consumption of high-energy-dense diets may lead to increased energy intake and weight gain, and evidence has been accumulating for an association between lower DED and better nutritional quality of the diet. In Swedish children and teenagers, it was found that low-e...
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Total Solar Eclipse Monday, August 21, 2017, all of North America will be treated to an eclipse of the sun.

Eclipse: Who? What? Where? When? and How? Total Solar Eclipse On Monday, August 21, 2017, all of North America will be treated to an eclipse of the sun. Anyone within the path of totalitycan see one of nature’s most awe-inspiring sights - a total solar eclipse. This path, where the moon will completely cover the sun and the sun's tenuous atmosphere - the corona - can be seen, will stretch from Lincoln Beach, Oregon to Charleston, South Carolina. Observers outside this path will s...
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Scientists at UT Southwestern Medical Center have developed a new technique using high-frequency alternating magnetic fields to heat artificial joints in the body

A short exposure to an alternating magnetic field might someday replace multiple surgeries and weeks of IV antibiotics as treatment for stubborn infections on artificial joints, new research suggests. Researchers at UT Southwestern Medical Center have shown that high-frequency alternating magnetic fields – the same principle used in induction cooktops – can be used to destroy bacteria that are encased in a slimy “biofilm” growing on a metal surface. The biofilm is a collection of microorganis...
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North Carolina State University Spheroid Stem Cell Production Sows Hope for IPF (Idiopathic Pulmonary Fibrosis)Treatment

In a small pilot study, researchers from North Carolina State University have demonstrated a rapid, simple way to generate large numbers of lung stem cells for use in disease treatment. This method of harvesting and growing a patient’s own lung stem cells shows promise in mice for treating idiopathic pulmonary fibrosis (IPF), and could one day provide human IPF sufferers with an effective, less invasive method of treatment for their disease. Idiopathic pulmonary fibrosis (IPF) is a chronic ir...
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University of Chicago genetically modified skin cells to produce glucagon-like peptide 1 (GLP1) protein that is beneficial in diabetes and obesity

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases. In the August 3, 2017 issue of the journal Cell Stem Cell, the researchers provide “proof-of-concept.” They describe gene-therapy administered through skin transplants to treat two related and extremely common human ailments: type-2 diabetes a...
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Drug developed at the University of Rochester Medical Center protected mice from non-alcoholic fatty liver disease

A drug developed at the University of Rochester Medical Center protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet – non-alcoholic fatty liver disease. In a study out today in the journal JCI Insights, scientists report that a drug called “URMC-099” reversed liver inflammation, injury and scarring in animals fed a diet high in fat, sugar and cholesterol. The diet was designed to replicate the Western fast food diet and recreate the features of non-alc...
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DIABETES SENTRY is a non-invasive, wearable electronic device which sounds an alarm when blood glucose threshold readings have been reached

The DIABETES SENTRY is an affordable, non-invasive, wearable electronic device which sounds an alarm while being worn on the wrist, ankle, or bicep of persons with diabetes whose blood glucose has begun to trend downward. In 90% of the cases, persons with diabetes show one or both of two hallmark symptoms of trending toward hypoglycemia, increased perspiration and a drop in skin temperature. This patient base is considered to be symptomatic. The 10% of individuals with diabetes that do NOT...
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Soft wearable robotic suit promotes normal walking in stroke patients, opening new approaches to gait re-training and rehabilitation

soft wearable robotic suit promotes normal walking in stroke patients, opening new approaches to gait re-training and rehabilitation Upright walking on two legs is a defining trait in humans, enabling them to move very efficiently throughout their environment. This can all change in the blink of an eye when a stroke occurs. In about 80% of patients post-stroke, it is typical that one limb loses its ability to function normally — a clinical phenomenon called hemiparesis. And even patients ...
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Salk Institute, Oregon Health and Science University (OHSU) and Korea’s Institute for Basic Science research scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.

EARLY GENE-EDITING SUCCESS HOLDS PROMISE FOR PREVENTING INHERITED DISEASES Scientists achieve first safe repair of single-gene mutation in human embryos Scientists achieve first safe repair of single-gene mutation in human embryos Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing. The technique, which uses the CRISPR-Cas9 system, corrected the mutation for a heart condition at the earliest stage of ...
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VCU Massey Cancer Center Scientists targeted the gene CtBP with a drug known as HIPP (2-hydroxy-imino phenylpyruvic acid) and were able to reduce the development of pre-cancerous polyps by half for colon cancer

Preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential “silver bullet” for preventing and treating it. The findings may extend to ovarian, breast, lung, prostate and potentially other cancers that depend on the same mechanism for growth. Led by Massey’s Deputy Director Steven Grossman, M.D., Ph.D., a team of scientists targeted the gene CtBP with a drug known as HIPP (2-hydroxy-imino phenylpyruvic acid) ...
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Lifeflo has developed oxygen producing small pouch/device for home care and remote patients.

Lifeflo has developed oxygen producing small pouch for home care and remote patients. FDA cleared device designed to provide oxygen at 6 Liters / Minute for 15-20 Minutes. No prescription is required and has a 3 year shelf life.  Within 60 seconds or less 99.9% oxygen is flowing.   Lifeflo™ products produce medical grade 99.9% oxygen utilizing their patent pending technology.  Each product allows to simply and affordably provide oxygen to anyone experiencing a challenging healt...
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Purdue University scientists have developed a new surgical glue that’s based on the proteins of sea mussels and other animals

Non-toxic glue modeled after adhesive proteins produced by mussels and other creatures has been found to out-perform commercially available products, pointing toward potential surgical glues to replace sutures and staples. More than 230 million major surgeries are performed worldwide each year, and over 12 million traumatic wounds are treated in the United States alone. About 60 percent of these wounds are closed using mechanical methods such as sutures and staples. “Sutures and staples have s...
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Rockefeller University Scientists use algorithm to peer through opaque brains

Trying to pinpoint signals from individual neurons within a block of brain tissue is like trying to count headlights in thick fog. A new algorithm, developed by researchers based at The Rockefeller University, brings this brain activity into focus. In research described June 26 in Nature Methods, the team, led by Rockefeller’s Alipasha Vaziri, used a light microscope-based technique to capture neural activity within a volume of mouse brain tissue at unprecedented speed. The algorithm allowed ...
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